Specialised Screens

LucenceINSIGHT™ Multi-Cancer Early Detection Screen

Health screening upgrade*
from S$ 598 incl. GST
added to a screening package
Standalone
from S$ 648 incl. GST
booked on its own

A single blood test can screen for signals linked to multiple cancers, using LucenceINSIGHT liquid-biopsy technology (circulating tumour DNA). If a signal is found, our doctor will guide you on the appropriate follow-up.

Recommended for individuals
With diet & lifestyle risk factorsWith a family history of cancerWanting to discuss early-detection options with a doctorWanting to be proactive about cancer risk

*The upgrade price applies when LucenceINSIGHT is added to a health screening package. It is an upgrade, not an add-on: the package's standard tumour-marker blood tests are swapped for the LucenceINSIGHT tests.

LucenceINSIGHT multi-cancer early detection blood test at New Path Medical
Early detection screen for 6 to 50 cancer types99% specificity in validation studies88% tumour-localisation accuracy in validation studiesEarly detection screen for 6 to 50 cancer types99% specificity in validation studies88% tumour-localisation accuracy in validation studies

Key takeaways

A liquid biopsy is a simple blood test that looks for circulating tumour DNA (ctDNA).LucenceINSIGHT screens for 6, 12 or up to 50 cancers, depending on the tier.It is a screening test, not a diagnosis; a positive signal needs confirmatory tests.It is developed by Lucence Diagnostics, a precision-oncology company based in Singapore.Results are typically ready in about 2 to 3 weeks.
What's included

Choose Your Tier

Three tiers of the LucenceINSIGHT range, differing by how many cancers are screened. Compare what each covers and review the right fit with our doctor.

Fasting
Not required
Other preparation
Try to avoid heavy meals 4 hours before the test
Sample
Blood
Package highlights
A single blood test for multiple cancer signals
Liquid-biopsy technology (ctDNA)
Comprehensive medical report and patient guidebook

All tiers include a comprehensive report. This screen does not replace recommended screening such as mammogram, colonoscopy or Pap smear.

6 cancer types
LucenceINSIGHT™ Core
HS upgrade*
S$ 598 incl. GST
added to a package
Standalone
S$ 648 incl. GST
booked on its own
Screens for 6 high-impact cancers that account for over 50% of global cancer mortality. [2]
Cancers screened (6)
ThyroidBreastLiverLungPancreaticColorectal
Up to 50 cancer types
LucenceINSIGHT™ Comprehensive
HS upgrade*
S$ 3,698 incl. GST
added to a package
Standalone
S$ 3,848 incl. GST
booked on its own
Screens for up to 50 cancer types using ctDNA with an added ctRNA boost. These cancers account for over 90% of global cancer mortality. [2]
Cancers screened (up to 50)

Covers up to 50 cancer types across head and neck, breast and thoracic, digestive, gynaecologic, blood, musculoskeletal, genitourinary and skin. Full list available below.

ctDNA + ctRNA boost included
12 cancer types
LucenceINSIGHT™ Women's / Men's
HS upgrade*
S$ 1,868 incl. GST
added to a package
Standalone
S$ 1,948 incl. GST
booked on its own
A wider, gender-specific panel screening for 12 cancers that account for over 70% of global cancer mortality. [2]
Screened for everyone (8)
Nasopharyngeal (EBV+)ThyroidStomachPancreaticGastrointestinal stromal tumour (GIST)ColorectalLungLiver
Men's panel adds (4)
OesophagealKidney (clear cell)BladderProstate
Women's panel adds (4)
BreastOvarianCervicalEndometrial

A ctRNA boost is available as a chargeable add-on to this tier.

*The upgrade price applies when LucenceINSIGHT is added to a health screening package. It is an upgrade, not an add-on: the package's standard tumour-marker blood tests are swapped for the LucenceINSIGHT tests.

The full list of 50 cancers
Full list of the 50 cancer types screened by LucenceINSIGHT Comprehensive
Understanding the test

How a Liquid Biopsy Works

What is a liquid biopsy?

A liquid biopsy is a blood test that checks for signals of cancer by looking for circulating tumour DNA (ctDNA), tiny fragments of DNA that tumours can shed into the bloodstream. Unlike a tissue biopsy, which removes a sample from a suspected tumour, a liquid biopsy needs only a routine blood draw, so it is minimally invasive and can screen for several cancers at once.

What are ctDNA and ctRNA?

Circulating tumour DNA (ctDNA) are fragments of DNA that tumours shed into the blood. Circulating tumour RNA (ctRNA) are cancer signals shed by living cancer cells. LucenceINSIGHT reads ctDNA and, in some tiers, adds a ctRNA boost to improve cancer-signal detection. The ctRNA boost is included with the Comprehensive (50) tier and is available as a chargeable add-on for the Women's / Men's (12) tier. It is most useful for people at higher risk, such as those with a family history of lung, colon or breast cancer, or heavy smokers.

How cancer signals (ctDNA and ctRNA) appear in the blood

Cancer signals in the blood: ctDNA shed by tumours and ctRNA shed by living cancer cells. Source: Lucence

How the test works

1
A small blood sample is collected into 2 to 3 special tubes.
2
The sample is sent to the lab, which analyses it for circulating tumour DNA (ctDNA).
3
If cancer-associated DNA signals are found, they are flagged in your written report.
4
Your doctor reviews the report with you and advises on any confirmatory tests, such as imaging or a tissue biopsy.
5
Results are typically ready in about 2 to 3 weeks, depending on the tier.

Why consider multi-cancer early detection?

In Singapore, about 1 in 4 people may develop cancer in their lifetime (Singapore Cancer Registry). Many cancers cause few or no symptoms early on, and only a handful have national screening programmes. A multi-cancer blood test widens the net, looking for signals across many cancers from a single draw, so that anything found can be looked into sooner.

Five-year cancer survival is higher when cancer is detected earlier

Earlier cancer detection saves lives. 5 year survival is higher when detected earlier. Source: Cancer Stat Facts. NIH NCI SEER. Accessed July 28, 2025. seer.cancer.gov/statfacts

What the screen can and cannot do

What it can do
Screen for signals of multiple cancers from one blood sampleOffer a minimally invasive option, needing only a blood drawBe repeated over time to support monitoring, guided by your doctor
What it cannot do
Diagnose cancer on its own; a signal needs confirmatory testsRule cancer out; a normal result does not guarantee you are cancer-freeReplace recommended screening such as mammogram, colonoscopy or Pap smear

Results are always interpreted alongside your history, symptoms and other findings, with your doctor.

How it compares to other cancer tests

Traditional tools such as mammogram, colonoscopy, Pap smear and imaging each focus on one area at a time and remain the standard for the cancers they cover.

However, national programmes cover only a few cancers. Around 8 in 10 cancer deaths involve cancers that common screening programmes do not cover, [3] and repeated tumour-marker testing can produce false positives over time. [4]

A liquid biopsy works differently: it screens broadly for signals across many cancers from a blood sample.

8 in 10 cancer deaths

involve cancers that common national screening programmes do not cover. [3]

About LucenceINSIGHT™

LucenceINSIGHT™ is developed by Lucence Diagnostics, a precision-oncology company headquartered in Singapore and Palo Alto. It uses proprietary technology to read circulating tumour DNA and/or circulating tumour RNA (ctRNA) from a blood sample. Its next-generation sequencing (NGS) method screens for up to 50 cancers with 99% specificity, meaning low false positives. [1]

99%
Specificity in validation studies [1]
88%
Tumour-localisation accuracy [1]
Up to 50
Cancer types screened
How it works

Meaningful Insights In 3 Simple Steps

Step 1: select your package online
1

Select your package online

Step 2: book your appointment in-clinic or home-based
2

Book in-clinic or home-based

Step 3: receive your report and review the results with the doctor
3

Receive your report, and review the results with the doctor once it's ready

Not Sure If This Is the Right Package?

Book an appointment and consult our doctor. We will help you decide whether this screen suits your age, history and risk factors.

Book appointment
Health screening packages
Upgrade Your Health Screening Package With LucenceINSIGHT™

Choose the upgrade price when you add LucenceINSIGHT to any of our health screening packages. The package’s standard tumour-marker blood tests are swapped for the LucenceINSIGHT tests.

GENERAL Screen
Your yearly baseline: essential biometrics and tests in an easy report.
S$ 198
incl. GST
GENERAL Screen
A fuller yearly picture, adding nutrition, hormones, cardiac risk and cancer markers.
S$ 398
incl. GST
GENERAL Screen
For adults who want a deeper look at their health. Endurance adds cardiac, inflammation and further cancer markers on top of Executive.
S$ 598
incl. GST
GENERAL Screen
A closer look at your hormonal and wellness markers. Elegance adds hormone testing, an H. pylori antibody check and an ultrasound scan on top of the Endurance profile.
S$ 798
incl. GST
GENERAL Screen
Our most complete health screen. Eminence covers the full Elegance profile and lets you customise with three additional scans or tests of your choice.
S$ 998
incl. GST
FAQ

Frequently Asked Questions

Does this screen diagnose cancer?

No. It screens for signals that may be associated with certain cancers, using circulating tumour DNA. A signal is not a diagnosis and needs confirmatory tests, which our doctor will guide you through.

How accurate is a liquid biopsy?

Accuracy varies by cancer type and stage. Liquid biopsy is generally better at picking up signals from more advanced cancers.

What is the difference between a liquid biopsy and a tissue biopsy?

A tissue biopsy takes a sample directly from a suspected tumour and is used to diagnose cancer. A liquid biopsy uses a blood sample to look for tumour DNA, and is used for screening and monitoring rather than diagnosis.

What are ctDNA and ctRNA?

Circulating tumour DNA (ctDNA) are DNA fragments that tumours shed into the blood; circulating tumour RNA (ctRNA) are signals shed by living cancer cells. LucenceINSIGHT analyses ctDNA, and adds a ctRNA boost in the Comprehensive tier (and as an add-on to the 12-cancer tier) to improve detection.

How is liquid biopsy better?

Liquid biopsies are less invasive and can be performed more frequently as a routine screening method.

Is the test painful? What sample is needed?

It needs only a routine blood draw so it is about as comfortable as any blood test.

What cancers does it screen for?

Core screens 6 common cancers; the Women’s / Men’s tier screens 12 cancers including gender-specific ones; and the Comprehensive tier screens up to 50 cancer types. The full list is shown above.

What does a normal result mean?

A normal result means no cancer-associated DNA signals were found in your sample, suggesting the absence of detectable cancer or insufficient ctDNA shedding. It does not guarantee you are cancer-free, so continue with your recommended routine screening and see your doctor about any symptoms.

Does this replace my usual cancer screening?

It is intended to complement recommended screening such as mammogram, colonoscopy and Pap smear, and may reduce the need for some tumour-marker blood tests. Discuss what is right for you with our doctor.

Is LucenceINSIGHT added on top of my health screening package?

It is an upgrade, not an add-on. When you choose the upgrade price, the standard tumour-marker blood tests in your health screening package are replaced by the LucenceINSIGHT liquid biopsy, rather than added on top. If you prefer to keep the package’s tumour markers and take LucenceINSIGHT separately, the standalone price applies.

When will results come back?

Typically about 2 to 3 weeks depending on the tier. We will let you know when your report is ready.

Can this be done home-based?

Yes. Home-based phlebotomy charges of $25 to $40 apply depending on your location in Singapore. WhatsApp us to schedule a home-based appointment.

Are consultation and follow-up charges included?

A comprehensive medical report prepared and reviewed by the doctor will be provided to you with clear information regarding your results and next steps required, should there be any abnormal findings.

We do recommend that you still consider reviewing your results with the doctor for further clarity and individualised advice. Kindly note that additional charges shall apply for consultations and/or treatments prescribed, as these are not included in the package prices listed.

References

Test-performance figures are from validation studies and may vary by cancer type, stage and population.

[1] Poh J, et al. J Clin Oncol. 2024;42(16):e15042 (specificity 99.0%; tumour-localisation accuracy 87.7%).

[2] Cancer-mortality coverage derived from GLOBOCAN 2022 and NIH NCI SEER (seer.cancer.gov/statfacts); conservative estimates.

[3] Bray F, et al. CA Cancer J Clin. 2024;74(3):229-263; MOH HealthHub Screen for Life (colorectal, cervical and breast are the cancers with national screening in Singapore).

[4] Croswell J, et al. Ann Fam Med. 2009;7(3):212-222 (cumulative false-positive risk across repeated screening).

Considering the LucenceINSIGHT™ Multi-Cancer Early Detection Screen?

$648 (Core), $1,948 (12) or $3,848 (Comprehensive), incl. GST · Single blood test · Home-based available. Ask our doctor whether it is right for you, or book today.